Rovectin - Anti-Irritant

Asta Cell Fortifier


Rovectin Anti-irritant Technology- Asta Cell Fortifier™

UV rays, pollution and even stress all cause oxidation, damaging your skin barrier over time. Asta Cell Fortifier™ (ACF) is rich in Astaxanthin, a powerful antioxidant extracted from microalgae that is naturally bright orange in color. Astaxanthin neutralizes reactive oxygen species (ROS), preventing the enzymatic breakdown of collagen and hyaluronic acid that leads to premature aging.

What are Free Radicals?
Free radicals are unpaired (free) electrons. They desperately search for another electron to pair with, and end up stealing electrons from the lipids in your skin. This creates a domino effect, and eventually damages your cell membranes, mitochondria and cellular DNA. This cascade damages precious skin lipids and weakens your skin barrier.

Powerful Antioxidant Astaxanthin
A potent antioxidant, Astaxanthin inhibits ROS to preserve your healthy skin barrier.

Astaxanthin facts:
• Antioxidant activity is 550 times stronger than Vitamin E
• Antioxidant activity is 550 times stronger than Green tea (catechin)
• Antioxidant activity is 850 times stronger than Coenzyme Q10
• Antioxidant activity is 6,000 times stronger than Vitamin C


Rovectin Anti-irritant Technology- Asta Cell Fortifier™ Clinical Data

Astaxanthin Cell Protection
Astaxanthin protected fibroblasts from damage by singlet oxygen

*Study Method: Human fibroblasts** were pre-incubated with Astaxanthin and then exposed to singlet oxygen. Protection was evaluated by cell viability by MTT method.
**Fibroblasts: Cells that constitute dermis and produce collagen and hyaluronic acid.


Age Spot Treatment
The age spot visibly reduced after 8 weeks treatment

*Study Method: 29 Healthy female subjects applied Astaxanthin topical product for 8 weeks. Comparison of age spots between 0 and 8 weeks were determined by image analysis.


Astaxanthin Repairs Wrinkles (By Analysis Methods with Replicas)
Wrinkle topography of the subject’s crow’s feet was evaluated with replica by image analysis before and after treatment


1. Tominaga et al., (2009). Cosmetic effects of astaxanthin for all layers of skin. Food Style 21, 13(10):25-29.
2. Tominaga et al., (2009). Protective effects of astaxanthin against singlet oxygen induced damage in human dermal fibroblasts in-vitro. Food Style 21, 13(1):84-86.
3. Cui Hang; Kong Yahui; Zhang Hong (2011). "Oxidative Stress, Mitochondrial Dysfunction, and Aging”
4. Further Reading
5. Camera et al., (2009). Astaxanthin, canthaxanthin and ß-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes. Exp Dermatol., 18(3):222-231.
6. Nishida et al., (2007). Quenching activities of common hydrophilic and lipophilic antioxidants against singlet oxygen using chemiluminescence detection system. Carotenoid Sci., 11:16-20.
7. Yamashita (2006). The effects of a dietary supplement containing astaxanthin on skin condition. Carotenoid Sci., 10:91-95.
8. Lee et al., (2003). Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IκB Kinase-dependent NF-κB activation. Molecules and Cells, 16(1):97-105.
9. Arakane (2002). Superior skin protection via astaxanthin. Carotenoid Sci., 5:21-24.
10. Lyons & O’Brien (2002). Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J. Derma. Sci., 30(1):73-84.
11. Yamashita (2002). Cosmetic benefit of the supplement health food combined astaxanthin and tocotrienol on human skin. Food Style 21, 6(6):112-117.
12. Seki et al., (2001). Effects of astaxanthin from Haematococcus pluvialis on human skin. Fragrance J., 12:98-103.
13. Black (1998). Radical Interception by carotenoids and effects on UV carcinogenesis. Nutrition Cancer., 31(3):212-217.
14. O’Connor & O’Brien (1998). Modulation of UVA light induced oxidative stress by beta-carotene, lutein and astaxanthin in cultured fibroblasts. J. Derma. Sci., 16(3):226-230.
15. Savoure et al., (1995). Vitamin A status and metabolism of cutaneous polyamines in the hairless mouse after UV irradiation: action of beta-carotene and astaxanthin. Int. J. Vit. and Nutr. Res., 65(2):79-86.
16. Yamashita (1995). Suppression of post UVB hyperpigmentation by topical astaxanthin from krill. Fragrance J., 14:180-185.